DX9 Mightron for me, no question.
Apollyon's proportions just seem off to me, especially his cannon, and I don't like the visible trigger on his legs. Despotron looks like he's wearing goalie pads on his legs, and his face sculpt isn't 'cartoon' enough for me.
Mightron has the best balance of proportions, cannon design, and face sculpt to make him the best choice for cartoon accuracy in my eyes.
While this doesn't show Apollyon, I made this comparison image to show just how close Mightron is to cartoon model.